{"id":1534,"date":"2024-04-25T13:33:32","date_gmt":"2024-04-25T05:33:32","guid":{"rendered":"https:\/\/www.51malin.com\/index.php\/archives\/1534"},"modified":"2024-04-25T13:33:32","modified_gmt":"2024-04-25T05:33:32","slug":"24-%e4%ba%8c%e7%a1%9d%e5%9f%ba-1-%e6%b0%9f%e8%8b%af","status":"publish","type":"post","link":"https:\/\/www.51malin.com\/index.php\/archives\/1534","title":{"rendered":"2,4-\u4e8c\u785d\u57fa-1-\u6c1f"},"content":{"rendered":"<p>    \t\t\t\t\t\t<img decoding=\"async\" src=\"http:\/\/staticv5.basechem.org\/img\/tupu\/old\/dc413707e8e2457294c877ca6af0c3fa.gif\" alt=\"2,4-\u4e8c\u785d\u57fa-1-\u6c1f\u7ed3\u6784\u5f0f\"><\/p>\n<p>\u7ed3\u6784\u5f0f<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">\u7269\u7ade\u7f16\u53f7<\/th>\n<td>01G3<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u5206\u5b50\u5f0f<\/th>\n<td>C6H3FN2O4<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u5206\u5b50\u91cf<\/th>\n<td>186.1<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u6807\u7b7e<\/th>\n<td>\n<p>                        2,4-\u4e8c\u785d\u57fa\u6c1f\u5316,<\/p>\n<p>                        \u6851\u683c\u8bd5\u5242,<\/p>\n<p>                        1-\u6c1f-2,4-\u4e8c\u785d\u57fa,<\/p>\n<p>                        \u4e8c\u785d\u6c1f,<\/p>\n<p>                        1-Fluoro-2-4-dinitrobenzene,<\/p>\n<p>                        1,3-Dinitro-4-fluorobenzene,<\/p>\n<p>                        Senger&#039;s Reagent,<\/p>\n<p>                        FNDP,<\/p>\n<p>                        \u82b3\u9999\u65cf\u542b\u6c2e\u5316\u5408\u7269\u53ca\u5176\u884d\u751f\u7269<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">\u7f16\u53f7\u7cfb\u7edf<\/a><\/li>\n<li><a href=\"#wx\">\u7269\u6027\u6570\u636e<\/a><\/li>\n<li><a href=\"#dl\">\u6bd2\u7406\u5b66\u6570\u636e<\/a><\/li>\n<li><a href=\"#st\">\u751f\u6001\u5b66\u6570\u636e<\/a><\/li>\n<li><a href=\"#fz\">\u5206\u5b50\u7ed3\u6784\u6570\u636e<\/a><\/li>\n<li><a href=\"#js\">\u8ba1\u7b97\u5316\u5b66\u6570\u636e<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                    <a href=\"\" class=\"dropdown-toggle\" data-toggle=\"dropdown\">\u66f4\u591a <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">\u6027\u8d28\u4e0e\u7a33\u5b9a\u6027<\/a><\/li>\n<li><a href=\"#zc\">\u8d2e\u5b58\u65b9\u6cd5<\/a><\/li>\n<li><a href=\"#hc\">\u5408\u6210\u65b9\u6cd5<\/a><\/li>\n<li><a href=\"#yt\">\u7528\u9014<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">\u7f16\u53f7\u7cfb\u7edf<\/h2>\n<p><b>CAS\u53f7\uff1a<\/b>70-34-8<\/p>\n<p><b>MDL\u53f7\uff1a<\/b>MFCD00007056<\/p>\n<p><b>EINECS\u53f7\uff1a<\/b>200-734-3<\/p>\n<p><b>RTECS\u53f7\uff1a<\/b>CZ7800000<\/p>\n<p><b>BRN\u53f7\uff1a<\/b>398632<\/p>\n<p><b>PubChem\u53f7\uff1a<\/b>\u6682\u65e0<\/p>\n<h2 id=\"wx\">\u7269\u6027\u6570\u636e<\/h2>\n<p><p>1.\u6027\u72b6\uff1a\u9ec4\u8272\u9488\u72b6\u7ed3\u6676\uff0c\u6db2\u5316\u540e\u4e3a\u6a59\u9ec4\u8272\u6db2\u4f53\u3002<sup>[1]<\/sup><\/p>\n<p>2.\u7194\u70b9\uff08\u2103\uff09\uff1a27.5~30<sup>[2]<\/sup><\/p>\n<p>3.\u6cb8\u70b9\uff08\u2103\uff09\uff1a178\uff083.33kPa\uff09\uff1b296<sup>[3]<\/sup><\/p>\n<p>4.\u76f8\u5bf9\u5bc6\u5ea6\uff08\u6c34=1\uff09\uff1a1.48<sup>[4]<\/sup><\/p>\n<p>5.\u9971\u548c\u84b8\u6c14\u538b\uff08kPa\uff09\uff1a0.32\u00d710<sup>-3<\/sup>\uff0825\u2103\uff09<sup>[5]<\/sup><\/p>\n<p>6.\u8f9b\u9187\/\u6c34\u5206\u914d\u7cfb\u6570\uff1a1.83<sup>[6]<\/sup><\/p>\n<p>7.\u95ea\u70b9\uff08\u2103\uff09\uff1a\uff1e110\uff08CC\uff09<sup>[7]<\/sup><\/p>\n<p>8.\u6eb6\u89e3\u6027\uff1a\u6eb6\u4e8e\u3001\u3001\u70ed\u3001\u4e19\u4e8c\u9187\u3002<sup>[8]<\/sup><\/p>\n<\/p>\n<h2 id=\"dl\">\u6bd2\u7406\u5b66\u6570\u636e<\/h2>\n<p><p>1\u3001\u6025\u6027\u6bd2\u6027\uff1a<\/p>\n<p>\u5c0f\u9f20\u53e3\u7ecfLCLo\uff1a50 mg\/kg\uff1b\u5c0f\u9f20Administration onto the skin LCLo\uff1a100 mg\/kg\uff1b\u5c0f\u9f20\u76ae\u4e0b\u6ce8\u5c04LCLo\uff1a100 mg\/kg\uff1b<\/p>\n<p>2\u3001\u81f4\u7a81\u53d8\uff1a<\/p>\n<p>\u6c99\u95e8\u6c0f\u83cc\u5728\u5fae\u751f\u7269\u65b9\u9762\u7684\u53d8\u5316\u6d4b\u8bd5\u7cfb\u7edf\uff1a5 ug\/plate\uff1b\u6c99\u95e8\u6c0f\u83cc\u5728\u5fae\u751f\u7269\u65b9\u9762\u7684\u53d8\u5316\u6d4b\u8bd5\u7cfb\u7edf\uff1a33 ug\/plate\uff1b\u7ec6\u83cc-Escherichia coli\u5728\u5fae\u751f\u7269\u65b9\u9762\u7684\u53d8\u5316\u6d4b\u8bd5\u7cfb\u7edf\uff1a5 umol\/L\uff1b<\/p>\n<p><strong>3.\u6025\u6027\u6bd2\u6027<strong><sup>[9]<\/sup><\/strong><\/strong>&nbsp; LD50\uff1a50mg\/kg\uff08\u5927\u9f20\u7ecf\u53e3\uff09<\/p>\n<p><strong>4.\u523a\u6fc0\u6027<\/strong>&nbsp; \u6682\u65e0\u8d44\u6599<\/p>\n<\/p>\n<h2 id=\"st\">\u751f\u6001\u5b66\u6570\u636e<\/h2>\n<p><p><strong>1.\u751f\u6001\u6bd2\u6027<\/strong>&nbsp; \u6682\u65e0\u8d44\u6599<\/p>\n<p><strong>2.\u751f\u7269\u964d\u89e3\u6027<\/strong>&nbsp; \u6682\u65e0\u8d44\u6599<\/p>\n<p><strong>3.\u975e\u751f\u7269\u964d\u89e3\u6027<strong><sup>[10]<\/sup><\/strong>&nbsp; <\/strong>\u7a7a\u6c14\u4e2d\uff0c\u5f53\u7f9f\u57fa\u81ea\u7531\u57fa\u6d53\u5ea6\u4e3a5.00\u00d710<sup>5<\/sup>\u4e2a\/cm<sup>3<\/sup>\u65f6\uff0c\u964d\u89e3\u534a\u8870\u671f\u4e3a420d\uff08\u7406\u8bba\uff09\u3002<\/p>\n<p><strong>4.\u5176\u4ed6\u6709\u5bb3\u4f5c\u7528<strong><sup>[11]<\/sup><\/strong><\/strong>&nbsp; \u8be5\u7269\u8d28\u5bf9\u73af\u5883\u6709\u5371\u5bb3\uff0c\u5e94\u7279\u522b\u6ce8\u610f\u5bf9\u6c34\u4f53\u7684\u6c61\u67d3\u3002<\/p>\n<\/p>\n<h2 id=\"fz\">\u5206\u5b50\u7ed3\u6784\u6570\u636e<\/h2>\n<p><p>1\u3001\u6469\u5c14\u6298\u5c04\u7387\uff1a39.33<\/p>\n<p>2\u3001\u6469\u5c14\u4f53\u79ef\uff08cm<sup>3<\/sup>\/mol\uff09\uff1a117.3<\/p>\n<p>3\u3001\u7b49\u5f20\u6bd4\u5bb9\uff0890.2K\uff09\uff1a325.3<\/p>\n<p>4\u3001\u8868\u9762\u5f20\u529b\uff08dyne\/cm\uff09\uff1a59.1<\/p>\n<p>5\u3001\u6781\u5316\u7387\uff0810-24cm3\uff09\uff1a15.59<\/p>\n<\/p>\n<h2 id=\"js\">\u8ba1\u7b97\u5316\u5b66\u6570\u636e<\/h2>\n<p><p>1.\u758f\u6c34\u53c2\u6570\u8ba1\u7b97\u53c2\u8003\u503c\uff08XlogP\uff09:\u65e0<\/P><\/p>\n<p>2.\u6c22\u952e\u4f9b\u4f53\u6570\u91cf:0<\/p>\n<p>3.\u6c22\u952e\u53d7\u4f53\u6570\u91cf:5<\/p>\n<p>4.\u53ef\u65cb\u8f6c\u5316\u5b66\u952e\u6570\u91cf:0<\/p>\n<p>5.\u4e92\u53d8\u5f02\u6784\u4f53\u6570\u91cf:\u65e0<\/p>\n<p>6.\u62d3\u6251\u5206\u5b50\u6781\u6027\u8868\u9762\u79ef91.6<\/p>\n<p>7.\u91cd\u539f\u5b50\u6570\u91cf:13<\/p>\n<p>8.\u8868\u9762\u7535\u8377:0<\/p>\n<p>9.\u590d\u6742\u5ea6:224<\/p>\n<p>10.\u540c\u4f4d\u7d20\u539f\u5b50\u6570\u91cf:0<\/p>\n<p>11.\u786e\u5b9a\u539f\u5b50\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:0<\/p>\n<p>12.\u4e0d\u786e\u5b9a\u539f\u5b50\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:0<\/p>\n<p>13.\u786e\u5b9a\u5316\u5b66\u952e\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:0<\/p>\n<p>14.\u4e0d\u786e\u5b9a\u5316\u5b66\u952e\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:0<\/p>\n<p>15.\u5171\u4ef7\u952e\u5355\u5143\u6570\u91cf:1<\/p>\n<\/p>\n<h2 id=\"xz\">\u6027\u8d28\u4e0e\u7a33\u5b9a\u6027<\/h2>\n<p><p><strong>1.\u7a33\u5b9a\u6027<sup>[12]<\/sup><\/strong>&nbsp; \u7a33\u5b9a<\/p>\n<p><strong>2.\u7981\u914d\u7269<sup>[13]<\/sup><\/strong> \u5f3a\u6c27\u5316\u5242\u3001\u5f3a\u78b1<\/p>\n<p><strong>3.\u907f\u514d\u63a5\u89e6\u7684\u6761\u4ef6<sup>[14]<\/sup><\/strong>&nbsp; \u53d7\u70ed<\/p>\n<p><strong>4.\u805a\u5408\u5371\u5bb3<sup>[15]<\/sup><\/strong>&nbsp; \u4e0d\u805a\u5408<\/p>\n<p><strong>5.\u5206\u89e3\u4ea7\u7269<sup>[16]<\/sup><\/strong>&nbsp; \u6c2e\u6c27\u5316\u7269\u3001\u6c1f\u5316\u6c22<\/p>\n<\/p>\n<h2 id=\"zc\">\u8d2e\u5b58\u65b9\u6cd5<\/h2>\n<p><p><strong>\u50a8\u5b58\u6ce8\u610f\u4e8b\u9879<sup>[17] <\/sup><\/strong>\u50a8\u5b58\u4e8e\u9634\u51c9\u3001\u901a\u98ce\u826f\u597d\u7684\u4e13\u7528\u5e93\u623f\u5185\uff0c\u5b9e\u884c\u201c\u53cc\u4eba\u6536\u53d1\u3001\u53cc\u4eba\u4fdd\u7ba1\u201d\u5236\u5ea6\u3002\u8fdc\u79bb\u706b\u79cd\u3001\u70ed\u6e90\u3002\u5305\u88c5\u5bc6\u5c01\u3002\u5e94\u4e0e\u6c27\u5316\u5242\u3001\u78b1\u7c7b\u3001\u98df\u7528\u5316\u5b66\u54c1\u5206\u5f00\u5b58\u653e\uff0c\u5207\u5fcc\u6df7\u50a8\u3002\u914d\u5907\u76f8\u5e94\u54c1\u79cd\u548c\u6570\u91cf\u7684\u6d88\u9632\u5668\u6750\u3002\u50a8\u533a\u5e94\u5907\u6709\u5408\u9002\u7684\u6750\u6599\u6536\u5bb9\u6cc4\u6f0f\u7269\u3002<\/p>\n<\/p>\n<h2 id=\"hc\">\u5408\u6210\u65b9\u6cd5<\/h2>\n<p><p>1.\u4ee52,4-\u4e8c\u785d\u57fa\u6c2f\u4e0e\u65e0\u6c34\u6c1f\u5316\u94be\u4e3a\u539f\u6599\uff0c\u7ecf\u4eb2\u6838\u53d6\u4ee3\u53cd\u5e94\u800c\u5f97\u3002<\/p>\n<p><img decoding=\"async\" src=\"http:\/\/images.basechem.org\/internal\/day_100925\/201009250957434972.gif\" alt=\"\" \/><\/p>\n<p>2.<span style=\"font-family:Arial\">\u5c06\u65e0\u6c34\u6c1f\u5316\u94be\uff0c\u4e8c\u7532\u57fa\u4e9a\u781c\u548c\u9002\u91cf\u963b\u805a\u5242\u6df7\u5408\uff0c\u63a7\u6599\u52a0\u70ed\u81f3120\u2103\uff0c\u7136\u540e\u52a0\u51652,4-\u4e8c\u785d\u57fa\u6c2f \uff3b \u5404\u53cd\u5e94\u7269\u7684\u914d\u6bd4\u4e3a2,4-\u4e8c\u785d\u57fa\u6c2f\u2236\u65e0\u6c34\u6c1f\u5316\u94be\u2236\u4e8c\u7532\u57fa\u4e9a\u781c\u2236\u963b\u805a\u5242\uff1d1.0\u22361.8\u2236 3.4\u22360.1\uff08 \u6469\u5c14\u6bd4)]\u3002\u7ef4\u6301\u53cd\u5e94\u6e29\u5ea6\u5728110\uff5e120\u2103\uff08 \u4e25\u683c\u63a7\u5236\u53cd\u5e94\u6e29\u5ea6\uff0c\u4ee5\u9632\u7206\u70b8\uff09 \uff0c\u53cd\u5e943h\uff1a<\/span><\/p>\n<p><img decoding=\"async\" src=\"http:\/\/images.basechem.org\/internal\/day_101009\/201010091013057917.gif\" alt=\"\" \/><\/p>\n<p><span style=\"font-family:Arial\">\u53cd\u5e94\u7ed3\u675f\u540e\u8fc5\u901f\u51b7\u5374\u81f3\u5ba4\u6e29\u3002\u62bd\u6ee4\u9664\u53bb\u6c1f\u5316\u94be\u6b8b\u6e23\uff0c\u6ee4\u6db2\u4e2d\u52a0\u6c34\u6d17\u6da4\uff0c\u9759\u7f6e\u540e\u5206\u53bb\u6c34\u5c42\uff08\u53ef\u56de\u6536\u4e8c\u7532\u57fa\u4e9a\u781c\uff09\uff0c\u6cb9\u5c42\u7531\u6c34\u6d17\u6da42\u6b21\uff0c\u4e8e2.73kPa\u4e0b\u51cf\u538b\u84b8\u998f\uff0c\u6536\u96c6176\uff5e180\u2103\u998f\u5206\uff0c\u5373\u4e3a\u6210\u54c12,4-\u4e8c\u785d\u57fa\u6c1f\u3002<\/span><\/p>\n<\/p>\n<h2 id=\"yt\">\u7528\u9014<\/h2>\n<p><p>1.\u7528\u4f5c\u5149\u5ea6\u6cd5\u6d4b\u5b9a\u6709\u673a\u80fa\u548c\u65b0\u9709\u7d20\u7b49\u7684\u663e\u8272\u5242\u3002\u8fd8\u7528\u4e8e\u5236\u5907\u6c1f\u79bb\u5b50\u9009\u62e9\u6027\u7535\u6781\u53ca\u81ea\u52a8\u6d41\u52a8\u6ce8\u5165\u52a8\u529b\u7535\u4f4d\u6cd5\u6d4b\u5b9a\u6251\u70ed\u606f\u75db\u3001\u5f02\u83f8\u80bc\u548c\u6c27\u4e19\u915a\u80fa\u3002\u7528\u4f5c\u8272\u8c31\u884d\u751f\u5316\u8bd5\u5242\uff0c\u7528\u4e8e\u4f2f\u80fa\u3001\u4ef2\u80fa\u3001\u9187\u3001\u915a\u3001\u786b\u9187\u3001\u54aa\u5511\u548c\u7fb0\u57fa\u5316\u5408\u7269\u7684\u6d4b\u5b9a\u3002<\/p>\n<p>2.\u7528\u4f5c\u86cb\u767d\u8d28\u5206\u6790\u7684\u8bd5\u5242\u4ee5\u53ca\u6d4b\u5b9a\u915a\u3001\u5417\u5561\u53ca\u6c28\u57fa\u9178\u3001\u919b\u3001\u809f\u7684\u8fd8\u539f\u5242\u3002<sup>[18]<\/sup><\/p>\n<\/p>\n<p>    \t\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/fascat4200-catalyst-dibutyltin-diacetate-arkema-pmc\/\">https:\/\/www.bdmaee.net\/fascat4200-catalyst-dibutyltin-diacetate-arkema-pmc\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/fentacat-d89-catalyst-cas108-13-7-solvay\/\">https:\/\/www.bdmaee.net\/fentacat-d89-catalyst-cas108-13-7-solvay\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/dibutyltin-monooctyl-maleate\/\">https:\/\/www.bdmaee.net\/dibutyltin-monooctyl-maleate\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.newtopchem.com\/archives\/39760\">https:\/\/www.newtopchem.com\/archives\/39760<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.cyclohexylamine.net\/epoxy-curing-agent-polyurethane-rigid-foam\/\">https:\/\/www.cyclohexylamine.net\/epoxy-curing-agent-polyurethane-rigid-foam\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/dabco-dc1-delayed-catalyst-dabco-dc1-delayed-strong-gel-catalyst-dabco-dc1\/\">https:\/\/www.bdmaee.net\/dabco-dc1-delayed-catalyst-dabco-dc1-delayed-strong-gel-catalyst-dabco-dc1\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/dabco-mp608-dabco-mp608-catalyst-delayed-equilibrium-catalyst\/\">https:\/\/www.bdmaee.net\/dabco-mp608-dabco-mp608-catalyst-delayed-equilibrium-catalyst\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/18.jpg\">https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/18.jpg<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/dabco-blx-11-polyurethane-foaming-catalyst-foaming-catalyst\/\">https:\/\/www.bdmaee.net\/dabco-blx-11-polyurethane-foaming-catalyst-foaming-catalyst\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a 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